D1.182 - Relationship between eHealth Literacy and Medication Adherence in Patients with Asthma: The Mediating Role of Self-Efficacy

To investigate the relationship between eHealth literacy and medication adherence among asthma patients, and to examine the mediating role of self-efficacy in this relationship.

A cross-sectional study was conducted among 486 asthma patients recruited from three tertiary hospitals between March and October 2024. Data were collected using the eHealth Literacy Scale (eHEALS), the Medication Adherence Rating Scale (MARS), and the General Self-Efficacy Scale (GSES). Pearson correlation analysis was performed to examine associations among variables. The PROCESS macro (Model 4) with bootstrap resampling (5000 iterations) was employed to test the mediating effect of self-efficacy.

 The mean scores of eHealth literacy, medication adherence, and self-efficacy were 28.63±6.42, 21.85±4.37, and 26.72±5.89, respectively. eHealth literacy was positively correlated with medication adherence (r=0.463, P<0.001) and self-efficacy (r=0.512, P<0.001). Self-efficacy was positively associated with medication adherence (r=0.538, P<0.001). Mediation analysis revealed that eHealth literacy exerted both direct (β=0.286, 95%CI: 0.182-0.390) and indirect effects (β=0.177, 95%CI: 0.118-0.246) on medication adherence through self-efficacy. The mediating effect accounted for 38.2% of the total effect.

Self-efficacy partially mediates the relationship between eHealth literacy and medication adherence in asthma patients. Healthcare providers should implement interventions targeting both eHealth literacy enhancement and self-efficacy improvement to optimize medication adherence in this population.