D3.51 - Cardiovascular System Problems in Children Athletes with Allergic Diseases

Pathologies of the cardiovascular system in allergic diseases are a global problem in the world's child population. Cardiovascular pathologies have increased in the population of athletic children. It occurs with equal frequency in both boys and girls. Especially during the transition period, the development of the disease is preceded by diseases of the respiratory system, infectious streptococcus and staphylococcus, pharyngitis, allergic diseases, diseases of the urinary system and gastrointestinal tract.

The aim of our study was to assess the problems caused by heart rhythm disturbances in children athletes with allergic diseases and to detect diseases in the child population. For the population study, we developed a formalized package of the MAP questionnaire, diagnostic criteria for the nosologies to be studied for screening, and an expanded questionnaire for the epidemiological study of diseases. The study was conducted in stages. The dynamics of morbidity were analyzed retrospectively, and at the next stage, the study of the spread and structure of the disease was based on screening a random and representative contingent of the population using a questionnaire. The study contingent consisted of 899 children aged 10 to 18 years. The study was carried out as a result of the 2022-2025 survey. Of these, 789 were boys, and 110 were girls. The standard set included allergy tests for food, plant, drug and household allergens. ECG and blood pressure were studied, and IgE levels were measured in some patients by the immunoenzymatic method. Also, clinical and laboratory studies were conducted with a certain contingent of 253 children, the results of children's clinical and allergological studies; Mathematical analysis of the study results was performed using Microsoft Excel 2010 and SPSS/V16.5 software package, and p<0.05 was taken as the critical value of reliability.

The age gradation of the studied population included arterial pressure and ECG data that were within the age norm, as a result of the examination, the need for further in-depth examination of the children was not observed. Children who personally agreed to participate in the study and whose parents were also not against it. Children could not be included in the control group, who had a history of allergic loads and other infectious diseases, diabetes. Children with atopic form, mild intermittent allergic diseases were selected as study subjects. The ECG signal was stored in the form of text files. The duration of registration for further analysis allowed us to determine the presence of extrasystoles and arrhythmias. Heart rhythm, cardiogram R-R interval sequence, registration was carried out on the bases taken by us (on the basis of G. Zhvania and M. Iashvili Pediatric Clinics). It was found that the differences between boys and girls in blood pressure (7.9%), R-R intervals (38.9%), respiration (36.8%), and heart rate (16.4%) are small and unreliable, and these data are within the age norm.

Based on clinical criteria, symptoms in a given population, in the event that there is no laboratory test that would actually determine the presence of such allergic atopy. Thus, the significance of the influence of each factor and its correlation with morbidity in the population were analyzed.