D3.35 - The influence of birth month on allergen sensitization patterns: A comprehensive analysis of skin prick test results in a large patient cohort

Allergic diseases represent a significant health concern globally, with a considerable impact on individuals' quality of life. Understanding the factors influencing allergen sensitization is crucial for effective prevention and management. This study aims to investigate potential associations between the birth month of patients and their sensitization patterns to common allergens, including birch, grass pollen, ragweed and mugwort pollen, house dust mites, as well as cat and dog epithelium. Exploring such correlations may contribute to the broader field of allergy research and provide insights into potential environmental influences on allergic sensitization.

The primary objective of this study is to assess whether there are significant differences in allergen sensitization based on the birth month of patients. By conducting skin prick tests on a large cohort of 2133 patients in the year 2022, we aimed to analyze the distribution of positive and negative test results across various birth months. 

Participants in this study consisted of 2133 patients who underwent skin prick testing in the year 2022. The study focused on assessing sensitization to common allergens, including birch, grass, mugwort and ragweed pollen, house dust mites, cat and dog dander. Statistical analysis involved the use of the Chi-square test to compare sensitization patterns among different birth months groups. Additionally, we  explored potential associations with other variables, such as monosensitization or polysensitization.

The analysis of sensitization patterns across different birth months groups did not reveal statistically significant differences for any of the tested allergens (p-value > 0.05). Additional analyses of monosensitization or polysensitization did not demonstrate significant variations based on birth month.

In conclusion, this study suggests that there is no significant impact of the birth month on allergen sensitization patterns among the studied cohort of patients. These findings contribute to the broader understanding of environmental factors influencing allergic sensitization. Further research may explore additional variables and larger cohorts to provide a more comprehensive picture of the complex interactions between birth month and allergic responses.