100478 - Cross-sectional study of vitamin D levels in the adult population of Kazakhstan

Despite the known nutritional sources of vitamin D and the involvement of sunlight in its production, the majority of the population living in the Almaty region, Kazakhstan, may have insufficient serum levels of 25-hydroxyvitamin D, even if we take into account the fact that public awareness of vitamin D deficiency is growing and most of the population is taking vitamin D. D in therapeutic dosages independently, without the appointment of the attending physician.

A cross-sectional study of the Almaty region among the adult population aged 18 years and older for 2022 was conducted. Vitamin D deficiency is considered to be a level of less than 10 ng/ml, a deficiency of 10-30 ng/ml, and a normal value of 30-100 ng/ml.

In 2022, 23,020 patients aged 18 and older of both sexes were examined, of which 13,707 were aged 18 to 39, 6,490 were aged 40-59, and 2,823 were over 60. According to the results of the study, it was revealed that the majority of the surveyed (14,329 – 62.25%) belong to the group of vitamin D deficiency and insufficiency, less than 30 ng/ml. About 37% of the patients had vitamin D levels within the acceptable range, and only a small part of the examined (0.54%) had hypervitaminosis. The average vitamin D level was 29.21 ng/ml, the median was 25.9 ng/ml, the maximum level was 156.1 ng/ml, and the minimum value was 3.3 ng/ml. It is also worth noting that the number of patients with vitamin D deficiency decreases with age.

As a result of the study, it was revealed that among the population of the Almaty region of Kazakhstan, a significant part of the adult population has insufficient vitamin D levels, despite the fact that this region is located in the southeastern part of Kazakhstan. Almaty has a lot of sunny days: up to 1596 hours a year. There are also up to 151 frost-free days per year. However, with age, there is a tendency to increase the number of patients with a normal level of 25(OH)D. Perhaps this trend is observed in connection with the treatment of the adult population to doctors, in particular endocrinologists, and the further determination of vitamin D concentration as a concomitant factor in various nosologies, with further adjustments and increases in vitamin D levels.